This project obtained funding in 2018-2019 and we hereby apply for continuing this project with funding for 2020. Efforts to reduce potential future health effects caused by persistent organic pollutants (POPs) ultimately calls for a better understanding of the factors that dictate human exposure. Using mechanistic models and human biomonitoring data, we have made significant progress in understanding temporality in human exposure [1, 2, 3]. Still, further research is critically needed for a better understanding of other factors that also affect human exposure . Building upon ongoing research and long-term collaboration within (and beyond) the Fram Centre, this project aims to explore how (i) human lipid dynamics (represented by body mass index; BMI) and (ii) spatial variability may influence human exposure in Norway. The activities during the two first years have focused on (i) compiling empirical results for time trends of POPs according to BMI categories for model comparison, (ii) implementing BMI code in the human module in an existing model framework, (iii) compilation of data on geographic variation along the Norwegian coast line for PCBs in fish (wild-caught salmon, cod and herring) and implications for human exposure. In 2020, the focus will be to carry out model predictions for PCB concentrations in cod and herring incorporating both temporal and spatial variability. Beyond the scientific value, this project will also be of relevance for national and international bodies for the regulation of chemicals as sound risk-management is not possible without a solid understanding of the link between emissions and human exposure.
Project manager: Therese Haugdahl Nøst / Ingjerd S. Krogseth
Project code: 442 672019